Toxic substances may exert their toxic effect directly on contact with the human body, often referred to as ‘local effects’. However, for a toxic substance to exert a ‘systemic effect’ they must enter and be absorbed by the body (Edwards, and Benke, 2013; Lee et al., 2017). OHS practitioners and Occupational Hygienists need to understand how toxic substances may exert their effects to protect worker health through the implementation of effective controls. You are the Occupational Hygiene Technician at a remote Lithium mine where the ore body is contained in alpha spodumene rock. In the processing plant where the ore is crushed, you are concerned about exposure to dust and noise. For each of these two workplace exposures, describe which body system may be affected, and for lithium (alpha-spodumene), dust illustrate the principles of absorption, distribution, metabolism, and excretion (Timbrell, 2008). For noise, describe how the exposure occurs, and the subsequent effects on the body systems. Your assignment should be structured as follows: Introduction & Background – Should include the aim of the assessment, a summary of the workplace and where / how workers may be exposed to the hazards identified. Chemical Hazard (lithium dust) Normal function of body system potentially affected Changes to body system after exposure (using ADME principles) Physical Hazard (noise) Normal function of body system potentially affected Changes to body system after exposure (using ADME principles) Conclusion To complete this assignment, you will need to access at least four (4) peer-reviewed scientific research articles to support your discussion. Word limit – 2500 (APA7th Referencing) Layout – Introduction& background, health hazard 1, health hazard 2, conclusion, referencing and citations.